Brothers with rare ‘Amitabh Bachchan's PAA disease' have captured million of hearts
Brothers, 13 and 9, with rare ‘Amitabh Bachchan's PAA disease' have captured million of hearts We all seen Amitabh Bachchan’s PAA, where he played a role 12-year-old boy with an extremely rare genetic disorder called progeria. Mentally he is twelve and very normal, but physically he looks five times older. Brothers, 13 and 9, with rare ‘Amitabh Bachchan’s PAA disease' have captured the hearts of millions in their fight to survive. Brothers, Nathan and Bennett Falcone, a dynamic pair who dab, play and joke just like any other kids their age. They have mandibuloacral dysplasia type B, the rarest form of a genetic condition that accelerates the aging of their cells to such an extent that sufferers have an approximate life expectancy of 13. If you have watched PAA movie, Auro's health begins to deteriorate as he reaches his 13th birthday, his physical defects catching up. They live in Erdenheim, Pennsylvania, with their parents and sister, refuse to sit back. They have just completed a clinical trial of a drug that has been shown to dramatically slow the progression of the disease. Progeria is a progressive genetic disorder that causes children to age rapidly, beginning in the first two years of their life. Children with progeria do not have any differing features at birth or during their first year, but as they reach two signs and symptoms such as slow growth and hair loss begin to appear. With time, their physical distinctions become more obvious. They remain much smaller than their peers, bald and frail. Progeria does not affect intellectual development. Progeria patients die of a heart attack or stroke, the most common age-related cause of death. As with elderly people, their cholesterol levels rise, their arteries harden, and their hearts struggle to pump blood in the same way as before - only that this all happens in their teens, rather than their 80s. -PTC NEWS
